Inventors: Gireesha T M, Sridev Mahopatra

This paper aims to improve the efficiency of genome editing using the CRISPR-Cas9 system and to explore novel sources of epigenetic variation in plants. The study focuses on optimizing CRISPR-Cas9 techniques to enhance precision, efficiency, and outcomes of genome editing in plant species. It also investigates how to harness epigenetic modifications to introduce new forms of genetic variation that can be used for plant improvement. The research includes developing new CRISPR-Cas9 variants or delivery methods, as well as examining the potential of epigenetic changes for creating beneficial traits in plants. The goal is to advance plant biotechnology by improving genome editing capabilities and expanding the scope of genetic and epigenetic variations available for crop enhancement.