Inventors: Dr. Arnab Banerjee, Dr. Indrani Talukdar

Investigating the significance of V2 and V3 variants of the gonadotropin-releasing hormone (GnRH) in hypothalamic and non-hypothalamic neurons provides new insights into neuronal physiology. These variants play crucial roles in regulating reproductive functions and broader neurological processes. Understanding their differential expression and functions in various neuronal populations informs research on fertility, neuroendocrinology, and neurodevelopmental disorders. Insights gained could lead to novel therapeutic approaches targeting GnRH variants for conditions affecting reproductive health and neurological function, advancing knowledge of GnRH signalling pathways and their implications in neuronal physiology beyond traditional reproductive roles. (Biological Science)