Inventors: Dr. Samit Chattopadhyay, Dr. Angshuman Sarkar

The transcriptional regulation of human telomerase (hTERT) by the chromatin remodeling protein SMAR1 involves intricate molecular mechanisms. SMAR1, also known as SMAR1 (scaffold/matrix attachment region-binding protein 1), interacts with specific regions of chromatin associated with the hTERT gene. It modulates the chromatin structure, influencing the accessibility of transcription factors.