Inventors: Dr. Indrani Talukdar, Dr. Arnab Banerjee

This paper investigates the molecular mechanisms of alternative splicing and the role of the regulator SMAR1 in TNF-α induced metabolic syndrome within mammalian skeletal muscle and hypothalamic neuronal cells. The study focuses on how TNF-α, a pro-inflammatory cytokine, triggers metabolic syndrome and alters splicing patterns of specific genes.