Inventors: Shibasish Chowdhury

Characterizing the binding affinity and internalization potential of Indian SARS-CoV-2 spike protein variants with hACE-2 involves both in-silico and in-vitro approaches. Computational simulations analyze molecular interactions between spike proteins and hACE-2 receptors, predicting binding affinities and identifying key binding sites. Concurrently, in-vitro experiments validate these predictions, assessing actual protein-protein interactions.